A theoretical investigation of the impact of a 2-dose vaccination strategy on Monkeypox transmission dynamics at population level

Abstract

In order to qualitatively evaluate the influence of a two-dose monkeypox (MPV) vaccination strategy when decreased human-to-human infection is accounted for, a new deterministic model for
MPV is created and implemented. The backward bifurcation phenomena is demonstrated to occur in the model as a result of the parameter that describes how quickly susceptible individuals receive their first dose of the MPV vaccination. Additionally, a distinct cutoff point for the rate at which vulnerable individuals receive the first dose of the MPV vaccination was discovered An example
of the model demonstrated that, in the absence of the rate at which susceptible individuals receive the first dose of the MPV vaccine, the disease-free equilibrium was globally asymptotically stable. The endemic equilibrium point of the distinguished case was also shown to globally asymptotically stable.